MT-45 | The JHI

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MT-45

Found in:  

Fentanyl

Type/Reason added:  

Synthetic Opioid

Relative Potency:  

1-3.5 times more potent than morphine (10,12)

Overview

The Effects

Treatment Options

Routes of Administration and Effects

Administration:

Can be administered orally, intranasally (insufflation), or via injection when dissolved in a liquid. The choice of route impacts the speed of onset and intensity of effects, with injection being the most rapid.

Dosage and Effects:

Opioid Effects: Pain relief, euphoria, relaxation, and drowsiness.

Adverse Effects: Dizziness, nausea, vomiting, constipation, respiratory depression, and confusion. Chronic use can lead to dependence and withdrawal symptoms, similar to other opioids.

Doses:

PO: 20-500 mg (majority of users limit at < 100 mg)
Insufflation: 1-50 mg
PR: 80 mg

Onset and Duration:

PO: 60 min after 45-70 mg dose
Insufflation: 15 min after 30 mg dose (12)
Duration: About 2h, re-dosing effects may be extended for over 8 h

Information Regarding the Substance

Physical Description:

MT-45 is generally a crystalline powder, but its exact appearance can vary depending on its source and purity. Impurities or cutting agents may alter its color or texture.

Side Effects:

Common: In addition to euphoria and sedation, users may experience itching, dry mouth, and a general sense of well-being. Some may also report ear problems, tingling or numbness, hand weakness, and balance issues.

Severe: Profound respiratory depression, unconsciousness, seizures, and in extreme cases, death. Long-term use has been associated with significant neurotoxicity, peripheral neuropathy, and hearing loss in some users.