THE J HEALTHCARE INITIATIVE
4-Fluorobutyryl Fentanyl
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Found in:
Fentanyl
Type/Reason added:
Synthetic opioid, Fentanyl analog / Opioid effects
Relative Potency:
about 1/8 of fentanyl, 7 times more potent than morphine
Treatment Options
Supportive Care: Immediate medical attention is crucial. Supportive care includes maintaining airway, breathing, and circulation.
Antidote: Naloxone (Narcan) is the primary antidote for opioid overdoses and can reverse the life-threatening effects of 4-Fluorobutyryl Fentanyl. Multiple doses of naloxone may be necessary due to the high potency and prolonged effects of fentanyl analogs.
Pharmacokinetics and Dynamics
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Metabolism: Metabolized primarily in the liver through the CYP3A4 enzyme pathway, followed by glucuronidation.
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Drug-Drug Interactions: High potential for interactions with other CNS depressants, increasing the risk of severe respiratory depression and death.
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