Treatment Options

Supportive Care: 

Oxygen therapy and other advanced life support measures may be required in severe cases.

Antidote: 

Naloxone (Narcan) is the primary antidote, though multiple doses may be necessary due to the potency of butyryl fentanyl. Emergency medical attention is crucial, as respiratory support may be needed.

Pharmacokinetics and Dynamics

Metabolism: 

Primarily metabolized in the liver, where it is broken down by enzymes such as CYP3A4, similar to fentanyl.

Drug-Drug Interactions: 

There is a high potential for dangerous interactions with other central nervous system depressants (e.g., benzodiazepines, alcohol, barbiturates), as they can compound respiratory depression and sedation.