THE J HEALTHCARE INITIATIVE
AH-7921
Found in:
Fentanyl,
Type/Reason added:
Opioid effects
Relative Potency:
similar to morphine (10)
Treatment Options
Supportive Care:
Immediate medical attention is necessary in the case of an overdose. Treatment includes maintaining the airway, providing respiratory support, and monitoring cardiovascular function.
Antidote:
Naloxone (Narcan) is the antidote for opioid overdose and can reverse the life-threatening effects of AH-7921. Due to its potency, multiple doses of naloxone may be required to counteract an overdose.
Pharmacokinetics and Dynamics
Metabolism:
Metabolized primarily in the liver, likely involving the cytochrome P450 (CYP) enzyme system, and excreted via the kidneys.
Drug-Drug Interactions:
Significant potential for dangerous interactions with other CNS depressants, such as alcohol, benzodiazepines, and other opioids, leading to increased sedation and risk of respiratory depression.
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