THE J HEALTHCARE INITIATIVE
5-Amino nitazene
Found in:
Fentanyl
Type/Reason added:
Nitazene (benzimidazole opioid)
Relative Potency:
N/A
Treatment Options
Supportive Care: Immediate medical attention is crucial. Supportive care includes maintaining the airway, ensuring proper breathing, and monitoring cardiovascular function.
Antidote: Naloxone (Narcan) is the primary antidote for opioid overdoses and can reverse the life-threatening effects of 5-Amino Nitazene. Due to its potency, multiple doses of naloxone may be required to counteract the effects.
Pharmacokinetics and Dynamics
Metabolism: Likely metabolized in the liver through pathways similar to other opioids, involving enzymes such as CYP450.
Drug-Drug Interactions: Significant risk of interactions with other central nervous system (CNS) depressants, such as alcohol, benzodiazepines, and other opioids, leading to increased potential for fatal respiratory depression.
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