Butonitazene (Item)

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Butonitazene

Found in:  

Fentanyl

Type/Reason added:  

Nitazene

Relative Potency:  

5 times stronger than morphine (18)

Overview

The Effects

Treatment Options

Supportive Care:

Intensive monitoring, oxygen therapy, and respiratory support may be necessary in severe cases, especially if naloxone does not work immediately.

Antidote:

Naloxone (Narcan) is the primary antidote for reversing opioid overdose. Due to butonitazene’s potency, multiple doses of naloxone may be required.

Pharmacokinetics and Dynamics

Metabolism:

Butonitazene is metabolized by the liver, though its specific metabolic pathways are not well-researched. It likely follows similar processes to other synthetic opioids.

Drug-Drug Interactions:

There is a high potential for dangerous interactions with other CNS depressants, including alcohol, benzodiazepines, or other depressants which can significantly increase the risk of severe respiratory depression and overdose.