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5-Amino nitazene

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Found in: 


Fentanyl

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Type/Reason added: 


Nitazene (benzimidazole opioid)

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Relative Potency: 


N/A

Treatment Options

Supportive Care: Immediate medical attention is crucial. Supportive care includes maintaining the airway, ensuring proper breathing, and monitoring cardiovascular function.

Antidote: Naloxone (Narcan) is the primary antidote for opioid overdoses and can reverse the life-threatening effects of 5-Amino Nitazene. Due to its potency, multiple doses of naloxone may be required to counteract the effects.

Pharmacokinetics and Dynamics

Metabolism: Likely metabolized in the liver through pathways similar to other opioids, involving enzymes such as CYP450.

Drug-Drug Interactions: Significant risk of interactions with other central nervous system (CNS) depressants, such as alcohol, benzodiazepines, and other opioids, leading to increased potential for fatal respiratory depression.

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