Supportive Care: The primary approach to managing acute benzodiazepine intoxication involves supportive care, including maintaining airway, breathing, and circulation.

Antidote: While flumazenil can reverse benzodiazepine effects, its use is typically not recommended due to the risk of precipitating withdrawal symptoms, lowering seizure threshold, and causing cardiac dysrhythmias. Flumazenil should be used with caution and only in specific cases where the benefits outweigh the risks.