2C Class Drugs & NBOMe

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Found in:  

MDMA (ecstasy)

Type/Reason added:  

Psychedelic phenethylamine / Mimic effects

Relative Potency:  N/A

Overview

The Effects

Treatment Options

Supportive Care: Maintain airway, breathing, and circulation.

Excited Delirium Management: Rapid sedation with benzodiazepines, fluid resuscitation, hyperthermia reduction. In severe cases, sedation, intubation, and extended paralysis with rocuronium or vecuronium may be necessary.

Antidotes: Generally supportive care; no specific antidote for many of these compounds.

Pharmacokinetics and Dynamics

Metabolism: Often involves CYP2D6 and CYP3A4 enzymes.

Drug-Drug Interactions: Potential inhibitory effects on monoamine oxidases, increasing the risk of toxicity when combined with other drugs.