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Tetrahydrofuranylfentanyl

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Found in: 


Fentanyl 

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Type/Reason added: 


Fentanyl Analog

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Relative Potency: 


20% of fentanyl

Description and Classification

Tetrahydrofuranylfentanyl:

A synthetic opioid and an analog of fentanyl. It belongs to the class of drugs known as fentanyl analogs, which are structural derivatives of fentanyl with modifications that typically enhance potency or alter pharmacokinetics. It acts primarily as a μ-opioid receptor agonist.

Relative Potency

Potency: 

Tetrahydrofuranylfentanyl is believed to be less potent than fentanyl itself but still far more potent than morphine. Estimates suggest it may be several times stronger than morphine but weaker than fentanyl, though exact comparative potency figures are limited.

Why It Is Added

Purpose

Medically, Tetrahydrofuranylfentanyl has no approved uses; it was developed as a research chemical and has emerged primarily in the illicit drug market. It is typically used recreationally for its opioid effects, such as euphoria and sedation, but has been associated with overdose deaths similar to other fentanyl analogs.

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