N-Desethyl Isotonitazene

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Found in:  

Fentanyl

Type/Reason added:  

Nitazene

Relative Potency:  

N/A

Overview

The Effects

Treatment Options

Description and Classification

N-Desethyl Isotonitazene:

A synthetic opioid and an active metabolite of isotonitazene, which belongs to the benzimidazole opioid class. These opioids are structurally distinct from fentanyl and morphine but bind strongly to the mu-opioid receptor, producing intense analgesic and euphoric effects.

Relative Potency

Potency:

N-Desethyl isotonitazene is estimated to be significantly more potent than morphine and comparable in strength to other benzimidazole opioids like isotonitazene and etonitazene. Although exact potency data is limited, isotonitazene itself is thought to be 500 times stronger than morphine, and its desethyl metabolite likely retains substantial activity.

Why It Is Added

Purpose

It is commonly mixed with or substituted for fentanyl in counterfeit pills or powders.