THE J HEALTHCARE INITIATIVE
Despropionyl Carfentanil
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Found in:
Fentanyl
Type/Reason added:
Inactive carfentanil-metabolite
Relative Potency:
N/A
Treatment Options
Supportive Care:
Maintain airway and provide respiratory support as needed.
Antidote:
Naloxone is effective in reversing opioid effects if significant receptor activity is present, though higher doses may be needed.
Pharmacokinetics and Dynamics
Metabolism:
Carfentanil is metabolized to despropionyl carfentanil (4-ANPP) via hepatic enzymes.
Drug-Drug Interactions:
There is a high potential for dangerous interactions with CNS depressants, alcohol, opioids, and CYP450 Enzyme Modulators
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