THE J HEALTHCARE INITIATIVE
Desmethylflunitrazepam
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Found in:
Fentanyl, BZD
Type/Reason added:
DBZD
Relative Potency:
N/A
Treatment Options
Supportive Care:
Maintain open airway and monitor respiratory status.
Antidote:
Flumazenil can reverse effects but must be used cautiously, as it may precipitate seizures in benzodiazepine-dependent individuals.
Pharmacokinetics and Dynamics
Metabolism:
Flunitrazepam is metabolized into desmethylflunitrazepam via hepatic enzymes. It further metabolizes and is excreted in urine. Its half-life varies but is generally shorter than that of flunitrazepam itself.
Drug-Drug Interactions:
There is a high potential for dangerous interactions with other CNS depressants, alcohol, opioids, and CYP450 modulators.
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