Treatment Furanyl UF-17

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Furanyl UF-17

Found in:  

Fentanyl

Type/Reason added:  

Synthetic opioid

Relative Potency:  

N/A

Overview

The Effects

Treatment Options

Supportive Care:

Oxygen therapy and airway management.

Antidote:

Naloxone is needed to reverse respiratory depression. Due to the potency of Furanyl UF-17, multiple doses of naloxone may be necessary.

Pharmacokinetics and Dynamics

Metabolism:

Furanyl UF-17 is metabolized in the liver, likely involving the cytochrome P450 enzyme system. Its metabolites are excreted primarily through the urine.

Drug-Drug Interactions:

Furanyl UF-17 has dangerous interactions with other central nervous system depressants, including alcohol, benzodiazepines, and other opioids. These combinations dramatically increase the risk of respiratory depression and fatal overdose. Drugs that inhibit or induce liver enzymes (e.g., CYP450 inhibitors or inducers) may also alter its metabolism and toxicity.