THE J HEALTHCARE INITIATIVE
Flubromazepam
Found in:
Fentanyl, BZD
Type/Reason added:
Long acting DBZD
Relative Potency:
N/A
Treatment Options
Supportive Care:
Monitoring vital signs and respiratory support if needed.
Antidote:
Flumazenil may be used in emergency settings to reverse the effects, although it carries a risk of precipitating withdrawal in dependent individuals.
Pharmacokinetics and Dynamics
Metabolism:
Flubromazepam is metabolized in the liver through the cytochrome P450 system, primarily CYP3A4. Its metabolites are excreted through the urine. The drug has a long half-life, leading to accumulation in the body with repeated dosing.
Drug-Drug Interactions:
Flubromazepam has significant interactions with other central nervous system depressants, such as alcohol, opioids, or barbiturates, greatly increasing the risk of sedation, respiratory depression, and overdose. It may also interact with inhibitors or inducers of CYP3A4, altering its metabolism and effects.
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