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4-Fluorobutyryl Fentanyl

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Found in: 


Fentanyl

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Type/Reason added: 


Synthetic opioid, Fentanyl analog / Opioid effects

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Relative Potency: 


about 1/8 of fentanyl, 7 times more potent than morphine

Treatment Options

Supportive Care: Immediate medical attention is crucial. Supportive care includes maintaining airway, breathing, and circulation.

Antidote: Naloxone (Narcan) is the primary antidote for opioid overdoses and can reverse the life-threatening effects of 4-Fluorobutyryl Fentanyl. Multiple doses of naloxone may be necessary due to the high potency and prolonged effects of fentanyl analogs.

Pharmacokinetics and Dynamics

  • Metabolism: Metabolized primarily in the liver through the CYP3A4 enzyme pathway, followed by glucuronidation.

  • Drug-Drug Interactions: High potential for interactions with other CNS depressants, increasing the risk of severe respiratory depression and death.

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