THE J HEALTHCARE INITIATIVE
Despropionyl Fentanyl
Found in:
Fentanyl
Type/Reason added:
Marginally active metabolite of fentanyl and fentanyl analogs
Relative Potency:
N/A
Description and Classification
Despropionyl Fentanyl:
A chemical precursor and minor active metabolite of fentanyl. It serves as an intermediate in the synthesis of fentanyl and related analogs. While it has some opioid receptor affinity, it is far weaker than fentanyl itself and not used clinically.
Relative Potency
Potency:
Despropionyl fentanyl is significantly less potent than fentanyl (hundreds of times weaker). Its pharmacological activity is minimal compared to fentanyl but may still contribute weakly to opioid effects if present in large amounts.
Why It Is Added
Purpose
Despropionyl fentanyl may be present as a contaminant in street fentanyl or related analogs due to incomplete synthesis.
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