Treatment Flubromazolam

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Flubromazolam

Found in:  

Fentanyl, BZD

Type/Reason added:  

Long acting DBZD

Relative Potency:  

N/A

Overview

The Effects

Treatment Options

Supportive Care:

Ensuring proper airway management and monitoring vital signs.

Antidote:

Flumazenil can reverse its effects in emergencies but carries risks of precipitating seizures or withdrawal symptoms in dependent individuals.

Pharmacokinetics and Dynamics

Metabolism:

Flubromazolam is metabolized in the liver, likely involving the cytochrome P450 system, particularly CYP3A4. Its metabolites are excreted primarily through the urine.

Drug-Drug Interactions:

Flubromazolam has significant interactions with other CNS depressants, including alcohol, opioids, barbiturates, and sedative-hypnotics. These combinations dramatically increase the risk of sedation, respiratory depression, and fatal overdose. It may also interact with drugs that inhibit or induce CYP3A4, altering its metabolism.