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Isotonitazene

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Found in: 


Fentanyl

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Type/Reason added: 


Nitazene

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Relative Potency: 


500 times stronger than morphine (18)

similar to fentanyl (24)

Description and Classification

Isotonitazene:

A synthetic opioid belonging to the benzimidazole class, structurally related to etonitazene. It acts as a potent agonist of the mu-opioid receptor, leading to effects similar to other opioids but with much higher potency.

Relative Potency

Potency: 

Isotonitazene is significantly more potent than morphine, with estimates suggesting it may be 500 times stronger, depending on individual metabolism and the specific preparation. It has been compared to fentanyl in potency but may vary depending on the dose and purity.

Why It Is Added

Purpose

It is used for its powerful euphoric and analgesic effects, often as a substitute for or an adulterant in heroin or counterfeit pills.

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